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| Antigenic Specificity | Phospho-TIRAP (Tyr86) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-TIRAP (Tyr86) Polyclonal Antibody. Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. |
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| Immunogen | n/a |
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| Other Names | TIRAP; MAL; Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein |
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| Gene, Accession # | Entrez: 114609; Uniprot: P58753 |
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| Catalog # | PA5-40297 |
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| Price | |
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| Order / More Info | Phospho-TIRAP (Tyr86) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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