1-334aa, Full length protein. MW: 38,224 Da. Purity >85% (SDS-PAGE). This gene encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding. Heterozygous missense mutations in this gene cause Duane s retraction syndrome 2 (DURS2). Multiple transcript variants encoding different isoforms have been found for this gene.