ChIP assay: 2 μg/million cells, Western Blot: 1:2500
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Description
YY1 Antibody (6H23L3), ABfinity? Rabbit Monoclonal. YY1 (transcriptional repressor protein YY1) is a multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Its effect on transcription regulation is depending upon the context in which it binds and diverse mechanisms of action including direct activation/repression, indirect activation/repression via a cofactor recruitment, or activation/repression by disruption of binding sites/conformational DNA changes. YY1's activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activ