PTPN6, Recombinant, Human, aa1-597, His-SUMO-Tag (Tyrosine-protein Phosphatase Non-receptor Type 6)
Description
Purity ~90% (SDS-PAGE). Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis. Source: Recombinant protein corresponding to aa1-597 from human PTPN6, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~79.1kD AA