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Description
Mouse monoclonal antibody to CD49f. GoH3 CD49f antigen monoclonal antibody reactive with mouse and human, is also called integrin alpha6, VLA-6 alpha Chains and platelet gpIc. CD49f is 120 kD transmembrane protein. CD49f contact with CD29 together, and integration Vegetarian beta A chain to form VLA-6 compleX; CD49f contact CD104 together with integrins beta 4 chain formed alpha 6 beta 4 CompleXes. CD49f is eXpressed on early T cells, monocytes, platelets, epithelial and endothelial cells. CD49f also be sent EXpression on germinal center B cells present. GoH3 antibodies to human, mouse, bovine cells, integrin alpha6 reaction. Such anti-The body has also been reported to block integrin alpha6 laminin binding functional activity