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Description
ZMIZ2 Polyclonal Antibody. ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
Immunogen
n/a
Other Names
HRIHFB2007, NET27, TRAFIP20, ZIMP7, hZIMP7; PIAS-like protein Zimp7; zinc finger MIZ domain-containing protein 2