| Edit |   |
|---|
| Antigenic Specificity | S100A12 |
|---|
| Clone | OTI1D1 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 μl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | S100A12 Monoclonal Antibody (OTI1D1). S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A12 is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. S100A12 is also a ligand for RAGE. Interaction with RAGE on mononuclear phagocytes, lymphocytes and endothelium triggers cellular activation. Nuclear factor kappa B, a key transcription factor for inflammatory events, is a |
|---|
| Immunogen | n/a |
|---|
| Other Names | CAAF1;CAGC;Calcitermin;Calcium binding protein in amniotic fluid;Calcium-binding protein in amniotic fluid 1;Calgranulin C;Calgranulin related protein;Calgranulin-C;CGRP;EN RAGE;EN-RAGE;ENRAGE;Extracellular newly identified RAGE-binding protein;MRP6;Neutrophil S100 protein;p6;Protein S100 A12;S100 calcium binding protein A12;S100 calcium-binding protein A12;S100A12;S10AC_HUMAN; |
|---|
| Gene, Accession # | Entrez: 6283; Uniprot: P80511 |
|---|
| Catalog # | MA5-25436 |
|---|
| Price | |
|---|
| Order / More Info | S100A12 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|