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| Antigenic Specificity | CDH4 |
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| Clone | OTI4F5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CDH4 Monoclonal Antibody (OTI4F5). N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium d |
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| Immunogen | n/a |
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| Other Names | Cadherin-4; Retinal cadherin; R-cadherin; R-CAD |
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| Gene, Accession # | Entrez: 1002; Uniprot: P55283 |
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| Catalog # | MA5-26686 |
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| Price | |
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| Order / More Info | CDH4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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