Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000
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Description
ABO Polyclonal Antibody. Histo-blood group ABO system transferase (NAGAT) is a member of the glycosyltransferase 6 family of proteins and the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B and H; the NAGAT protein functions as the basis of this group. A, B and AB individuals express a glycosyltransferase activity converting the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), while O individuals do not express this glycosyltransferase activity. The B phenotype of NAGAT differs from the A form by a few residue substitutions, whereas the O form is a result of a single base frame-shift deletion in the N-terminal extremity of the gene.
Immunogen
n/a
Other Names
A transferase, Abo, ABO blood group (transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase), ABO glycosyltransferase, B (A) alpha 1, 3 glactosyltransferase, B transferase, BGAT, Fucosylglycoprotein 3 alpha galactosyltransferase, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha N acetylgalactosaminyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Fucosylglycoprotein alpha-N-acetylgalactos