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Description
Mouse Anti-Lypd8 Recombinant Antibody (CBYJL-2575). Provided herein is a Mouse monoclonal antibody, which binds to Ly6/Plaur Domain Containing 8 (Lypd8). The antibody can be used for immunoassay techniques, such as FC. Lypd8 encodes a member of the Ly6/PLAUR family of cysteine-rich proteins that plays an important role in the protection of colonic epithelium from flagellated microbiota. LY6/PLAUR domain containing 8 undergoes proteolytic processing to generate a mature, glycosylphosphatidylinositol-anchored protein that is localized to the apical surface of the colonic epithelial cells. Mice lacking LY6/PLAUR domain containing 8 are sensitive to chemically induced intestinal inflammation.
Immunogen
Mouse Lypd8-transfected cells.
Other Names
2210415F13Rik; ly6/PLAUR domain-containing protein 8