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Description
Mouse Anti-LYPD6B Recombinant Antibody (CBYCL-594). Provided herein is a Mouse monoclonal antibody against Human LYPD6B. The antibody can be used for immunoassay techniques, such as WB, IHC-P. LYPD6B is believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-33:beta-42 nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-32:alpha-5:beta-42 nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.