Immunofluorescence: 5 μg/mL, Western Blot: 1 μg/mL
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Description
PAR6 Polyclonal Antibody. This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 domain and a semi-Cdc42/Rac interactive binding domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen
n/a
Other Names
PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40, PAR-6 alpha; Tax-interacting protein 40; partitioning defective 6 homolog alpha; partitioning defective-6 homolog alpha; partitioning-defective protein 6; tax interaction protein 40