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Description
APBB3/FE65L2 Polyclonal Antibody, Cy5.5 Conjugated. ? Target Background: Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the ?-Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of ?-Amyloid. Via its ability to control the intracellular accumulation of ?-Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, iso
Immunogen
KLH conjugated synthetic peptide derived from human APBB3/FE65L2. Immunogen Range: 440-480/486
Other Names
Amyloid beta A4 precursor protein binding family B member 3; Amyloid beta A4 precursor protein-binding family B member 3; amyloid beta precursor protein binding family B member 3; amyloid precursor interacting protein; Apbb3; APBB3_HUMAN; Fe65 like protein 2; FE65L2; Protein Fe65-like 2; SRA.