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| Antigenic Specificity | HP1 alpha |
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| Clone | 7E3 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | peroxidase (HRP) conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HP1 alpha Monoclonal Antibody, HRP Conjugated. ? Target Background: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
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| Immunogen | KLH conjugated synthetic peptide derived from human HP1 alpha |
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| Other Names | Antigen p25; HP1-α; CBX5; CBX5_HUMAN; Chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox homolog 5; Chromobox protein homolog 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1 homolog alpha; HP1 alpha; HP1 alpha homolog; HP1; HP1A; HP1Hs alpha. |
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| Gene, Accession # | Gene ID: 23468, SwissProt: P45973 |
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| Catalog # | bsm-33377M-HRP |
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| Price | |
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| Order / More Info | HP1 alpha Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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