Immunocytochemistry: Assay-Dependent, Immunofluorescence: Assay-Dependent, Western Blot: 1:5000-1:20,000
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Description
HP1 alpha Polyclonal Antibody. This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same pr
Immunogen
n/a
Other Names
HP1, HP1A, HP1 alpha homolog, HP1-ALPHA, HP1Hs alpha, antigen p25, chromobox homolog 5 (HP1 alpha homolog, Drosophila), chromobox protein homolog 5, heterochromatin protein 1 homolog alpha, heterochromatin protein 1-alpha