產(chǎn)品名稱(chēng) FK 506 from TOCRIS BIOSCIENCE
    產(chǎn)品貨號(hào) 3631/10
    產(chǎn)品價(jià)格 現(xiàn)貨詢(xún)價(jià),電話:010-67529703
    產(chǎn)品規(guī)格 10 mg
    產(chǎn)品品牌 TOCRIS BIOSCIENCE
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameFK 506
    DescriptionPotent calcineurin (protein phosphatase 2B) inhibitor that requires FK 506-binding protein 12 (FKBP12) for activity (IC50 = 3 nM). Inhibits secretion of IL-1, IL-2 (IC50 = 1 nM), IL-3, IL-4, IL-6 (IC50 = 35 nM), GM-CSF, TNFα (IC50 = 10 nM), IFNγ and Myc from activated T cells in vitro. Exhibits potent immunosuppressive, neuroprotective and anticonvulsant activity in vivo. Analog also available.. Purity 99%. MW (observed): 804.02
    Size10 mg
    Concentrationn/a
    Applicationsn/a
    Other Names(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-e. Tacrolimus, Fujimycin
    Gene, Accession, CAS #CAS: 104987-11-3
    Catalog #3631/10
    Price
    Order / More InfoFK 506 from TOCRIS BIOSCIENCE
    Product Specific ReferencesPubMed: 21273417, 22902539, 23141069, 23386250, 23918927, 23989619, 24667246, 24973091, 25071439, 25558061, 25810886, 26589795, 27246912, 27340371, 27545504
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