IGFBP6 contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Recombinant human IGFPB6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW: 25 kDa (236 aa, 28-240 aa + His Tag), confirmed by MALDI-TOF. Purity ≥85%
Size
20 μg
Concentration
0.5 mg/ml
Applications
RUO
Other Names
Insulin-like growth factor-binding protein 6, IBP6