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Description
Bub1 Polyclonal Antibody, Alexa Fluor? 555 Conjugated. ? Target Background: Serine/threonine-protein kinase that performs 2 crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the assembly of checkpoint proteins at the kinetochore, being required for the subsequent localization of CENPF, BUB1B, CENPE and MAD2L1. Required for the kinetochore localization of PLK1. Plays an important role in defining SGOL1 localization and thereby affects sister chromatid cohesion. Acts as a sub
Immunogen
KLH conjugated synthetic peptide derived from human Bub1. Immunogen Range: 980-1030/1085