A reversible, cell-permeable inhibitor of the motor protein Eg5, blocking basal ATPase activity in vitro (IC50 = 6.1 μM) and inducing the formation of monoastral spindles in cell-based assays (IC50 = 51.3 μM)
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
254753-54-3 inhibitors cells cycling cancers cell-permeable permeable motor proteins Eg5 kinesin family 11 Kif11 Kif-11 Kif 11 ATPases in vitro arrests mitosis induces inducer mitotic arrest death tumors reversible monoastral spindles microtubule assembly checkpoint cycles