A potent and selective antagonist of the group II metabotropic glutamate receptors mGluR2 and mGluR3 (IC50s = 21 and 14 nM, respectively); less effectively blocks mGluR8 and mGluR7 (IC50s = 173 and 990 nM, respectively) can be effectively used in isolated cells, tissues, and in vivo
Size
1 mg
Concentration
n/a
Applications
n/a
Other Names
LY 341495 LY-341495 neurosciences receptors antagonists mGluR2 mGluR3 mGluRs 2 3 two three mGluR-2 mGluR-3 metabotropic glutamates groups II LY-341495 Lys 341495 isolated cells tissues in vivo blood brains blood-brain barrier mGlu2/3 mGlu-2/3 mGlus 2/3