An N-terminal extended tyrosinated analogue of α-CGRP; binds to AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respectively); binds to and stimulates cAMP accumulation in rat L6 myocytes (IC50 = 4 nM; EC50 = 12 nM); binds to rat brain and spleen membrane preparations (IC50s = 0.2 and 0.5 nM, respectively); induces positive chronotropic and inotropic effects in isolated right and left guinea pig atria (EC50s = 282 and 74 nM, respectively); inhibits the twitch response in rat vas deferens (EC50 = 1.9 nM),