1-14aa; Full length protein. MW: 1,759 Da. Purity ≥90%. This protein, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.
[Recombinant Angiotensinogen (AGT); Angiotensinogen; Serpin A8 Cleaved into the following 3 chains: 1. Angiotensin-1; Angiotensin I; Ang I Angiotensin-2; Angiotensin II; Ang II Angiotensin-3; Angiotensin III; Ang III Des-Asp[1]-angiotensin II ]
Gene, Accession, CAS #
AGT; SERPINA8; Ang I; Ang II; Ang III, Accession: P01016.1