MW: 68,758 Da. Purity >85% (SDS-PAGE). This protein is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
Size
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Concentration
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Other Names
[aryl hydrocarbon receptor nuclear translocator-like protein 1; Aryl hydrocarbon receptor nuclear translocator-like protein 1; aryl hydrocarbon receptor nuclear translocator-like protein 1; Brain and muscle ARNT-like 1]