bovine, canine, human, mouse, nonhuman primate, rat
Isotype
n/a
Format
purified
Size
50 ug
Concentration
n/a
Applications
Western Blot: 0.1-1 μg/mL
Reviews / Ratings
If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Phospho-HDAC7 (Ser155) Polyclonal Antibody. Histone deacetylase 7 is a thymus-specific, intracellular transcription factor belonging to the class IIa histone deacetylase family. Reports suggest that dephosphorylation and nuclear localization of HDAC-7 is promoted by myosin phosphatase, thus regulating the repression of Nur77 and inhibition of apoptosis in CD4+CD8+ double-positive thymocytes. HDAC-7 plays a specific role in maintaining vascular integrity by repressing the expression of matrix metalloproteinase (MMP) 10. It promotes repression mediated by transcriptional corepressor NCOR2 and is an efficient corepressor of the androgen receptor (AR). It is also responsible for the deacetylation of lysine residues on the N-terminal part of the