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Description
ZMIZ1 Polyclonal Antibody. Retinoic acid plays a critical role in development, cellular growth, and differentiation and induces the expression of a variety of genes. RAI17 expression is induced by retinoic acid and is predominantly expressed in heart, brain and ovaries. Within brain, highest expression is in amygdala. The deduced 1,067-amino acid protein contains an MSX-interacting zinc finger (MIZ) domain, a nuclear localization signal sequence, and 2 proline-rich regions. A strong intrinsic transactivation domain is identified in the C-terminal proline-rich region. RAI17 expression is detected in various cancer cell lines. RAI17 colocalizes with endogenous androgen receptor (AR) in the nuclei of prostate epithelial cells from human tissue
Immunogen
n/a
Other Names
RP11-519K18.1, MIZ, RAI17, TRAFIP10, ZIMP10, hZIMP10; FLJ00092 protein; RP11-519K18.1; retinoic acid induced 17; zinc finger MIZ domain-containing protein 1; zinc finger-containing, Miz1, PIAS-like protein on chromosome 10