An NSAID and diethylene glycol ester form of flufenamic acid; inhibits lipoxygenase isolated from guinea pig leukocytes (IC50 = 5.3 μM) and production of PGE2 in stimulated rat peritoneal macrophages; reduces acetic acid-induced vascular permeability in mice and UV-induced erythema in guinea pigs in a dose-dependent manner at doses ranging from 40-320 and 5-20 mg/kg, respectively; inhibits inflammation in a rat model of adjuvant-induced arthritis; decreases the pain response in a silver nitrate-induced rat model of arthritis and the acetic acid-induced writhing test in mice, indicating analgesic activity
Size
250 mg
Concentration
n/a
Applications
n/a
Other Names
B 577 B577 Bay-d 1107 Bayrogel Glasel Reumon Rheumon TV 485 Traumon WHR 5020 WHR5020 antiinflammatory TV485 d1107 nonsterodial