Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (aa 1029-1249)
Clone
P3G4AT
Host Species
Mouse
Reactive Species
human
Isotype
n/a
Format
unconjugated
Size
20 μg
Concentration
n/a
Applications
ELISA,Western Blotting (WB)
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Description
CD45 leukocyte common antigen (LCA) belongs to the family of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portion of these molecules has protein phosphatase activity and is involved in regulation of transmembrane signalsSynonyms: Leukocyte common antigen, EC 3.1.3.48, L-CA, T200, CD45 antigen, PTPRC, LCA, LY5, B220, CD45, GP180
Immunogen
Anti-human CD45 mAb is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CD45 AA 1029-1249