Glutathione S-transferase omega 1, Recombinant, Human
Description
Purity ≥95% (SDS-PAGE). Recombinant GSTO1 comprises a 241 amino acid fragment (1-241) corresponding to the GSTO1 mature protein, which is expressed in E. coli with an amino-terminal hexahistidine tag. GSTO1 is a member of the theta class glutathione S- transferase-like (GSTTL) protein family. GSTO1 is expressed in a wide range of human tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities and also catalyzes the reduction of monomethylarsonate, an intermediate in the pathway of arsenic biotransformation. GSTO1 protects from oxidative stress, a risk factor for Alzheimer disease, vascular dementia and stroke. Applications: Suitable for use in ELISA.