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Description
p70 S6 kinase alpha Polyclonal Antibody, Alexa Fluor? 680 Conjugated. ? Target Background: Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex. Upon mitogenic stimulation, phosphoryla
Immunogen
KLH conjugated synthetic peptide derived from human p70 S6 kinase alpha. Immunogen Range: 280-330/525