Immunoprecipitation: 2-10 μg/mg lysate, Western Blot: 1:2,000-1:10,000
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Description
WNK1 Polyclonal Antibody. WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
Immunogen
n/a
Other Names
Kinase deficient protein, Protein kinase lysine deficient 1, Protein kinase with no lysine 1, Serine/threonine protein kinase WNK1