Immunohistochemistry: 1:300-1:2000, Western Blot: 1:300-1:2000
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Description
Rhodopsin Polyclonal Antibody. Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal. Abs(max)=495 nm. Rod shaped photoreceptor cells which mediates vision in dim light. Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region. Defects in RHO are the cause of retinitis pigmentosa type 4 (RP4). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lo