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Description
RASGRF1 (Ser929) Polyclonal Antibody, Alexa Fluor? 594 Conjugated. ? Target Background: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathwa
Immunogen
KLH conjugated synthetic phosphopeptide derived from human RasGRF1 around the phosphorylation site of Ser929