An anticancer agent; inhibits the growth of Calu-6 NSCLC and A-375 melanoma cell lines (EC50s = 10 and 25 μM, respectively); induces arrests the cell cycle at the G2/M phase and induces apoptosis of Calu-6 cells in a concentration-dependent manner; induces non-apoptotic growth arrest in HUVECs and inhibits VEGF-, FGF-, and EGF-induced endothelial cord formation in vitro (EC50s = 47, 103, and 34 nM, respectively); reduces hemoglobin content and blood vessel density in a Matrigel? plug model of neoangiogenesis; reduces tumor growth in a dose-dependent manner in a Calu-6 mouse xenograft model