α2-adrenoceptor agonist that does not cross the blood brain barrier. Displays ~ 120-fold selectivity for α2 receptors over α1 receptors and acts predominantly at non-α2A-adrenoceptors which may be of the α2C subtype. Antinociceptive; increases tail-flick latencies in Sasco and Harlan rats. Purity 99%. MW (observed): 253.77