A SMO agonist that can promote the differentiation of multipotent mesenchymal progenitor cells into osteoblasts (EC50 = 1.2 μM); used to characterize a novel SMO active site since it does not recognize the classic cyclopamine binding site utilized by other SMO agonists
Size
50 mg
Concentration
n/a
Applications
n/a
Other Names
smoothened SMO agonists stems cells differentiation receptors signaling signals quinolinecarboxamides derivatives multipotent mesenchymal progenitors osteoblasts cyclopamine binding sites binds active GSA10 GSA-10 genes regulations transduction research GSAs