A potent endocannabinoid uptake inhibitor (IC50s = 10 and 283 nM for AEA and 2-AG, respectively, in U937 cells); inhibits AEA uptake in FAAH-deficient HMC-1 human mast cells and Neuro2a mouse neuroblastoma cells (IC50s = 137 and 55 nM, respectively); increases AEA and 2-AG levels by 1.5-fold in mouse brain but not peripheral tissues (10 mg/kg, i.p. for seven days); induces a typical tetrad of hypothermia, catalepsy, analgesia, and hypomotility in mice