產(chǎn)品名稱 AT-13148 from BIOVISION, INC.
    產(chǎn)品貨號(hào) B1144-5
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
    產(chǎn)品規(guī)格 5 mg
    產(chǎn)品品牌 BIOVISION, INC.
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameAT-13148
    DescriptionAT13148 is a potent, ATP-competitive multi-AGC kinase inhibitor that displays antitumor activity. AT13148 blocks AKT, p70S6K, PKA, ROCK, and SGK substrate phosphorylation inducing concentration dependent apoptosis in cancer cells. It also shows anti-tumor efficacy in HER2-positive, PIK3CA-mutant BT474 breast, PTEN-deficient PC3 human prostate cancer and PTEN deficient MES-SA uterine tumor in xenografts. Gene expression studies shows that AT13148 has a predominant effect on apoptosis genes. MW: 313.78. Purity ≥98% by HPLC
    Size5 mg
    Concentrationn/a
    Applicationsn/a
    Other Names(S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2-amino-1-(4-chlorophenyl)ethanol
    Gene, Accession, CAS #CAS: 1056901-62-2
    Catalog #B1144-5
    Price
    Order / More InfoAT-13148 from BIOVISION, INC.
    Product Specific Referencesn/a
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