A pan-Aurora kinase inhibitor (IC50 = 3 nM for both Aurora A and B). AT9283 also potently inhibits several kinases including the JAK2 and 3 (IC50's 1.2 and 1.1 nM, respectively), c-Abl(IC50 = 110 nM) and Abl/T315I (IC50 = 4 nM). MW: 381.43. Purity ≥98% by HPLC