Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (aa 32-429)
Clone
4G5
Host Species
Mouse
Reactive Species
human
Isotype
IgG1
Format
ascites
Size
100 μL
Concentration
n/a
Applications
ELISA,Western Blotting (WB)
Reviews / Ratings
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Description
NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Immunogen
Purified recombinant extracellular fragment of human NTRK3 (AA 32-429) fused with hIgGFc tag expressed in HEK293 cells.