An inhibitor of PRMT6 (IC50 = 10 nM) that less potently targets PRMT1 and PRMT8 (IC50s = 119 and 223 nM, respectively); dose-dependently decreases methylation of the PRMT6 substrate H3R2 in A375 cells transiently expressing PRMT6 (IC50 = 0.637 μM)
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
EPZ-020411 pyrazole protein arginine methyltransferase PRMT 6 PRMT6