A cell-permeable non-steroidal antagonist of the estrogen receptor GPER (Ki = 20 nM); displays low affinity cross-reactivity with the classical estrogen receptor, ERα, so that at doses greater than 1 μM it is capable of mediating limited ER-dependent transcriptional activity
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
receptors antagonist cancers diabetes bones-related research bones related GPER g protein coupled estrogen protein-coupled GPR30 GPR-30 GPRs 30 non-steroidal nonsteroidal non steroidal antagonists estrogens ERs G15 Gs 15 G-15 antidepressive anti depressive anti-depressive in vivo