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Description
Keratin 19 is a type I keratin. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically found in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. Synonyms: Monoclonal Keratin K19 antibody, Anti Keratin K19 antibody, Cytokeratin 19 antibody.
Immunogen
Keratin K19 antibody was raised in mouse using Keratin K19 of Mr 40 000 from cultured human MCF-7 cells as the immunogen.