A hypoglycemic agent; stimulates insulin and somatostatin release from perfused rat pancreas in a dose-dependent manner at concentrations ranging from 0.03-3 μM; increases intracellular Ca2+ in individual rat pancreatic β-cells; reduces blood glucose by 20% in fasted mice; inhibits glucose-induced hyperglycemia in normal rats, genetically diabetic KK mice, and in a mouse model of streptozotocin-induced diabetes,