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Description
Pyk2 (Tyr402) Polyclonal Antibody, HRP Conjugated. ? Target Background: Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, a
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Pyk2/PTK2B around the phosphorylation site of Tyr402. Immunogen Range: 370-420/1009