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Description
IRF3 (Ser396) Polyclonal Antibody. ? Target Background: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and lat
Immunogen
KLH conjugated synthetic phosphopeptide derived from human IRF3 around the phosphorylation site of Ser396. Immunogen Range: 375-425/427