ChIP assay: 5 μg x 10^6 cells, Immunocytochemistry: 1 μg/mL, Immunofluorescence: 1 μg/mL, Western Blot: 1 μg/mL
Reviews / Ratings
If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Histone H3 Antibody, ABfinity? Rabbit Oligoclonal. Histone octamers are an essential component of the nucleosomal complex with key roles in chromatin packaging and target gene transcription. They undergo various post-translational modifications including methylation, acetylation and phosphorylation to facilitate chromatin regulation. Modified histones display varied distribution patterns at the heterochromatin and the euchromatin, hence defining actively transcribed or repressed genes in the eurochromatin and the 'silenced' loci in the heterochromatin. These modifications in turn serve as epigenetic markers for transcriptional status of a gene and landing sites for transcriptional complexes, fundamental to understanding several biolog