Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
Reviews / Ratings
If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Cdc6 Polyclonal Antibody. CDC6 encodes a protein that is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
Immunogen
n/a
Other Names
CDC18L, HsCDC18, HsCDC6, CDC6, p62(cdc6), cdc18-related protein, CDC6-related protein, CDC6 cell division cycle 6 homolog, cell division control protein 6 homolog, cell division cycle 6 homolog (S. cerevisiae)