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Description
Rabbit IgG Monoclonal antibody for Q14258 detection. Tested positive for WB IHC IF/IF IP FC in Human Mouse Rat
Immunogen
A synthesized peptide derived from human TRIM25 Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.