Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
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Description
ABCE1 Polyclonal Antibody. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
Immunogen
n/a
Other Names
ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I, 2'-5'-oligoadenylate-binding protein, ATP-binding cassette sub-family E member 1, RNase L inhibitor, huHP68, ribonuclease 4 inhibitor, ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor