WM8 is a metastatic human melanoma cell line. This cell line features the specific N818K mutation in the c-KIT gene. This cell line expresses wild type BRAF, PTEN, N-RAS, and CDK4 genes. WM8 cells produce xenograft tumors when injected into immunocompromised mice.
Size
1 mL
Concentration
10.0 million cells/ml
Applications
The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways.
Other Names
Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft